10x Genomics : Introduces Atera
TXG
Published on 04/18/2026 at 10:14 pm EDT
Only on Atera
April 2026
The future belongs to spatial biology
Biology functions through specific cells, expressing
specific molecules, in specific locations within a tissue
SPATIAL BIOLOGY
Preserving the full context
Tissue
Histology, H&E, IHC
Cells
Microscopy, Flow Cytometry
Molecules
Sanger, qPCR, NGS
SPATIAL BIOLOGY
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Current spatial tools require compromises
Throughput at Low Resolution
Plex at Low Performance Performance at Low Plex and
Plex
Throughput Performance
Plex
Throughput Performance
Low Throughput
Plex
Throughput Performance
Until now…
© 10X GENOMICS, INC. 2026 | FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES.
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Uncompromised spatial
Plex
Whole transcriptome profiling
Throughput
Up to 800 whole transcriptome samples of 1 cm2 per year
Performance
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Single cell level sensitivity and specificity at subcellular resolution
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REDEFINING HOW BIOLOGY IS MEASURED AND UNDERSTOOD
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© 10X GENOMICS, INC. 2026 | FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES. 6
Spatial without compromise
Xenium paved the way - Atera redefines spatial biology from a
specialized tool into a primary, standalone discovery engine
Discovery Power
Whole transcriptome coverage with sensitivity fine-tuned for each target
Output
Engineering advancements to enable large-scale, routine projects
Confidence
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Data quality comparative to Chromium single cell
Accessibility
Standard slide compatibility and reduced cost-per-sample
The Atera Whole Transcriptome Assay (WTA)
Built on our Chromium and Visium expertise, this highly sensitive probe-based assay bypasses poly-A limitations to deliver superior whole transcriptome discovery
Unlock FFPE
Probes deliver whole transcriptome coverage even
for fragmented transcripts and degraded samples
Single-cell quality
Delivers gold-standard sensitivity comparable to Chromium single-cell, with subcellular spatial resolution
Tunable sensitivity
Poly-A capture often misses lowly expressed genes
Pinpoint specificity
Refined padlock probe chemistry ensures high on-target calls and low false discovery rates compared to other ISH methods
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Assays to fit every use case
Start broad Zoom In Customize
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Atera WTA
Ultimate spatial discovery
18,000+ gene panels with
stackable customization of up to 1,000 genes
Human WTA at launch
Mouse WTA coming soon
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Atera Select
Targeted expression validation
Stackable 1,000-gene panels
(combine up to 3 panels to 3,000 targets)
Human multi-tissue at launch
Additional tissue and
application panels coming soon
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Custom
Unlimited exploration
Build bespoke modular assay
with up to 3,000 gene targets
Target any sequence in any
species
Stack up to three 1,000-gene
Custom or Atera Select panels for modular flexibility
© 10X GENOMICS, INC. 2026 | FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES. 9
Atera brings new scale to spatial biology along multiple dimensions
Larger sample area
>5 cm2 per slide - Fit more samples or map large continuous sections
Slide compatibility
Off-the-shelf, standard microscopy
slides for sample preservation
Discovery at scale
~800 Whole Transcriptome samples of 1 cm2 per year
Large cohort profiling
>3,000 mid-plex samples of 1 cm2 with a 1,000-gene panel per year
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Achieving the Impossible: Innovations Behind Atera
Imaging Power: Maximum Throughput
Built-for-purpose, ultra-fast high-res optical system
Chemistry: Optimized Assays
Redesigned for high sensitivity and maximum insight at whole transcriptome scale
Fluidics: Best of Both Worlds
Speed, efficiency, and standard microscopy slides
Compute: Petabytes to Insights
Onboard GPUs and advanced algorithms translate raw sensor data in real time
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Throughput for the future of spatial transcriptomics
Unlocking Clinical Trial Operational Efficiency:
3,000 core biopsies in a single year (4 mm diameter FFPE)
Whole
transcriptome
4 instruments
188 runs
Xenium Prime 5K
8 cores per slide, 376 slides
42 runs
1 instrument
1 FTE
2-4 FTEs
18 cores per slide, 176 slides
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Redefining Spatial Biology with Atera
Plex
Whole transcriptome profiling
Throughput
Up to 800 whole transcriptome samples of 1 cm2 per year
Sensitivity & Specificity
All at subcellular resolution
© 10X GENOMICS, INC. 2026 | FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES.
© 10X GENOMICS, INC. 2026 | FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES. 13
Disclaimer
10x Genomics Inc. published this content on April 18, 2026, and is solely responsible for the information contained herein. Distributed via Public Technologies (PUBT), unedited and unaltered, on April 19, 2026 at 02:13 UTC.