DuPont Expands Bioprocessing Portfolio with Launch of DuPont AmberChrom TQ1 Chromatography Resin

Published: 2025-05-22 11:51:00 ET DD

Published on 05/22/2025 at 11:51

DuPont has expanded its bioprocessing portfolio with the launch of DuPont AmberChrom TQ1 chromatography resin for the purification of oligonucleotides and peptides in support of a wide-range of biopharma applications. The new agarose-based chromatography resin offers increased loading capacity, higher throughput, and requires less pressure than comparable competing products within the same class. These characteristics make DuPont AmberChrom TQ 1 chromatography resin an excellent choice for high resolution separations and polishing, offering high purity fractions in biomolecule purifications and the separation of closely-related impurities from target molecules.

Its low-pressure build-up, combined with high-yield and purity for peptides and both DMT-Off and DMT-On oligonucleotides, makes the resin suitable for use in benchtop and large-scale commercial purifications. To support the introduction of the resin, DuPont has published comprehensive internal application studies that used real-world drug feeds to validate performance characteristics; this documentation can also assist with the integration of the product into processes at every phase from drug discovery through commercialization. DuPont??

AmberCh Chrom?? TQ1 chrom chromatography resin can be used in combination with existing AmberChrom?? XT and CG chromatography resins to purify various oligonucleotides, or for the crude purification of peptide feeds in preparation for reverse phase chromatography.

DuPont introduced the new chromatography resin to the market during TIDES USA--a conference dedicated to accelerating oligonucleotide and peptide innovations. Hadi Fares, Ph.D, a bioprocessing application scientist with DuPont, presented application studies to demonstrate the performance capabilities of DuPont?? Amber Chrom??

TQ1 Chromatography resin, and how it complements existing resins within the DuPont bioprocessing portfolio. On June 19, 2025, DuPont will host an educational webinar discussing the capabilities of DuPont??mberChrom?? T First Quarter chromatography resin and how its loading capacity and purification efficacy can enhance purification of oligon nucleotides and peptides.

Learn more about DuPont?? AmberCh chromatography resin and the broader DuPont bioprocessed portfolio. As a global market leader in adsorbents and ion exchange resins with over 80 years of experience, DuPontbioprocessing solutions can accelerate and enhance the discovery and production of small molecule synthetics,oligonucleotides, and peptides, as well as diagnostics, by enabling complicated separations that help companies achieve their vision to manage and treat diseases.