Pacira BioSciences : Corporate Sustainability Report (pacira corporate sustainability report 2024 v1 20260430)

Published: 2026-04-30 20:06:13 ET PCRX

Published on 04/30/2026 at 08:06 pm EDT

2024 | CSR Report

‌About

Pacira delivers innovative, non-opioid pain therapies to transform the lives of patients. Pacira has three commercial-stage non-opioid treatments: EXPAREL® (bupivacaine liposome injectable suspension), a long-

acting local analgesic currently approved for infiltration, fascial plane block, and as an interscalene brachial plexus nerve block, an adductor canal nerve block, and a sciatic nerve block in the popliteal fossa for postsurgical pain management; ZILRETTA® (triamcinolone acetonide extended-release injectable suspension), an extended-release, intra-articular injection indicated for the management of osteoarthritis knee pain; and iovera®º, a

novel, handheld device for delivering immediate, long-

acting, drug-free pain control using precise, controlled doses of cold temperature to a targeted nerve. The company is also advancing the development of PCRX-201 (enekinragene inzadenovec), a novel locally administered gene therapy with the potential to treat large prevalent diseases like osteoarthritis.

Table of

ABOUT 2

CEO LETTER 3

COMPANY OVERVIEW 4

PUTTING PATIENT & PRODUCT SAFETY FIRST 6

EMPOWERING EMPLOYEES TO THRIVE 8

COMMITMENT TO OUR COMMUNITIES &

OPIOID-SPARING INNOVATION 16

PROMOTING ENVIRONMENTAL RESPECT 26

OPERATING ETHICALLY WITH HIGH INTEGRITY 29

SUSTAINABILITY ACCOUNTING STANDARDS

BOARD (SASB) INDEX 33

2024 Corporate Sustainability Report

I am proud to be a part of building a longterm sustainable business that contributes to the broader healthcare, scientific, and global community as outlined in this report. Pacira operates within an ecosystem driven by a commitment to patients, to science, and to our people - it is this pledge that allows us to positively impact the world around us.

In 2021, Pacira began its journey to accelerate the pace of sustainable practices by reinforcing our commitment to human and labor rights and

increasing transparency around our longstanding internal policies regarding bioethics, patient safety, and responsible marketing.

During that time, the Company released its Global Human and Labor Rights Policy to increase transparency into long-standing policies that protect and respect the rights of our employees, stakeholders, and communities. Concurrently,

we updated our Supplier Code of Conduct to ensure that our suppliers are aligned with both the requirements and the spirit of Pacira's Global Human and Labor Rights Policy.

In June 2021, the Pacira board of directors formally assumed oversight of our Sustainability efforts.

Our Nominating, Governance and Sustainability Committee was tasked with creating, implementing, and supervising an industry leading Environmental, Social and Governance platform.

Over the last several years, we have released updated policies reaffirming our long-standing commitment to Global Health and Safety, Global Labor and Human Rights, Bioethics, and Expanded Access.

In 2024, our Compensation Committee tied nearly one third of our corporate goals around Culture and People. This includes investment in

employee development and advancement of our Environmental, Social and Governance programs. We are committed to intentionally cultivating a culture we call One Pacira, grounded on key values and behaviors that enable our organization to function as a united team. We seek to foster an environment of inclusion where all feel welcomed and valued for their backgrounds, perspectives, and experiences while holding one another accountable to promote trust and transparency

in support of our communities and collective mission.

While we have achieved much, our work is not yet done. We're driving opioid-sparing innovation every day to provide better ways to manage pain safely and effectively, with a commitment to our patients, our culture, and our communities which are at the core of everything we do."

Best Regards,

Frank D. Lee

Chief Executive Officer & Director

2024 Corporate Sustainability Report

MISSION

We deliver innovative non-opioid pain therapies to transform the lives of patients.

Pain; Injury/trauma

(Regenerative medicine) OA pain

Pre-surgical pain

('Prehabilitation')

Acute surgery

Rehabilitation

Recovery

Commercial

Development

Enekinragene inzadenovec (PCRX-201)

WE'RE WORKING TO MEET THE NEEDS OF

HEALTHCARE PRACTITIONERS AND THEIR PATIENTS

We are pioneering safe and effective opioid-sparing innovation to improve the patient journey along the neural pain pathway

Our in-depth knowledge of non-opioid pain management, coupled with our passion for delivering improved patient care, drives our commitment to provide solutions that address unmet medical needs and improve clinical results.

CULTURE

At Pacira, we have a capable and passionate team of people dedicated to serving our customers in a work environment that encourages collaboration. Our culture inspires and challenges individuals to be effective and efficient in all that they do.

We are committed to intentionally cultivating a culture of inclusion where all feel welcomed and valued for their backgrounds, perspectives, and experiences. We hold one another accountable to promote trust and transparency in support of our communities and collective mission.

Pacira is setting

n e w e xpec tations

for CLINICIANS

and PATIENT S alike

LOW- and NO-OPIOID

PAIN MANAGEMENT

through innovative

alternatives that

offer BETTER OUTCOMES

We believe the era of opioids as the industry standard for pain management IS OVER

GUIDING PRINCIPLES

Keep the patient at the center

Pain is deeply personal, often overwhelming even the simplest daily tasks. Every decision we make is grounded in the needs and experiences of our patients.

Follow the science

Science is the foundation upon which we build our innovations, ensuring safety, efficacy, and meaningful outcomes.

Treat our people well

Our team is our strength. Fairness, respect, and equity are the cornerstones of our culture, creating a supportive environment where everyone can thrive.

VALUES

Every day, we are determined to achieve the extraordinary

Integrity is the foundation of who we are

We respect diverse talent and the collective power

of a unified team

2024 Corporate Sustainability Report

We are committed to conducting our clinical trials in accordance with high bioethical standards and clinical guidelines

All Research and Development (R&D) activities at Pacira, including all clinical trials, are conducted in conformance with the Principles of Good Clinical Practice (GCP) as defined by the International Conference on Harmonization of Technical Requirements for Pharmaceuticals

for Human Use, and international ethical standards―in particular the Helsinki Declaration on ethical principles regarding human experimentation. Any employees or third parties involved in clinical trials sponsored by Pacira are trained to follow Good Clinical Practices.

Our R&D activities are designed to ensure that all participants enrolled have given their free and informed consent (or assent if applicable) to participate in a trial, either directly or via their legally authorized representative. Study participants and/or their legal representatives must understand the purpose of any R&D activity so that they are able to make an

informed decision about whether to participate. Regardless of the objective, all R&D activities are designed primarily to protect the safety and wellbeing of participants and to guarantee that they or their legal representatives give their voluntary consent/assent based on straightforward and comprehensive information that is expressed in easily understandable, non-technical language,

especially for any participants who may be considered vulnerable for any reason.

We have established multiple policies and standard operating procedures under the guidance and oversight of our Chief Medical Officer and Chief Legal and Compliance Officer, to ensure a high level of ethics in scientific

and medical activities, better stakeholder engagement, and greater transparency.

An independent ethics committee reviews and approves proposed R&D protocols before any clinical trial may begin. Our risk management

framework helps us monitor any potential risks to our high quality and safety standards. Potential risks may be identified through audits of our sponsored clinical trials―both internally and of our external partners.

Details regarding how we manage potential ethical challenges and risks associated with R&D, how we manage and audit our clinical trials, and our commitment to R&D transparency can be found in our Policy on Bioethics.

Rigorous manufacturing and quality control

Pacira is committed to upholding all applicable manufacturing regulations and best practices through rigorous quality control and quality assurance protocols. All our products are manufactured in accordance with current Good Manufacturing Practice (cGMP) regulations

enforced by the U.S. Food and Drug Administration as overseen by our quality management team.

In addition to our own internal quality controls, requirements for our suppliers have been designed to ensure a consistent production process

that prioritizes patient safety and high-quality standards.

This comprehensive approach to patient safety and quality control allows us to deliver our products safely and effectively.

Robust safety monitoring and pharmacovigilance practices

It is our policy to:

Comply with all applicable legal and worldwide regulatory requirements for handling safety information and product complaints

Continually monitor safety information and product complaints regarding the use or our marketed or investigational products and take appropriate actions to minimize risk to patients

Communicate important safety findings to clinical investigators, healthcare professionals, and regulatory agencies in a timely manner

All employees, partners, suppliers, contractors, vendors, and consultants are required to report any safety information and/or product complaints they receive to the Company, as well as complete regular training on obligations to report safety

information in their respective roles in service to our company.

More details regarding our pharmacovigilance practices, including how we monitor the quality, safety, and security of our products, can be found in our Policy on Patient and Product Safety.

We are committed to thoughtful, conscientious, and patient-focused interactions with both the public and the broader healthcare community

Our external interactions, with both patients and providers, conform to our high medical, scientific, and ethical standards, and comply with all applicable laws, regulations, and industry guidance. They also conform to our core values, which prioritize patient safety and honesty. In addition to our own policies, we abide by applicable guidelines and codes established by national industry associations, as well as by major international industry associations. These codes and guidelines supplement applicable government regulation and provide guidance and self-discipline for ethical marketing practices. In the United States, we

abide by the PhRMA Code on Interactions with Healthcare Providers (HCPs), the PhRMA Guiding Principles on Direct-to-Consumer Advertising

of Prescription Medicines, the OIG Compliance Program, and the AdvaMed Code on ethical interactions and relationships with HCPs.

More details regarding our approach to engagement with the healthcare community, including promotional engagement with HCPs and patients, can be found in our Policy on Responsible Marketing.

Consideration, Mutual Respect, and Diversity are Fundamental to our Success

One of the foundations of our corporate culture is that consideration, mutual respect, and diversity are all fundamental elements for success. We are dedicated to protecting the rights of women and minority groups, as well as advocating for the equal treatment and protection of rights for all of our employees, directors, contractors, customers, and stakeholders, without regard to sex, race, color, religion, creed, gender identity, sexual orientation, marital status, age, national origin, citizenship, genetic information, physical or mental disability, or membership or application for membership in a uniformed service.

We are

c ommit t ed to intentionally cultivating a

culture of inclusion

where all feel

WELCOMED and

VALUED

for their backgrounds, perspectives, and experiences

We hold one another accountable

to promote TRUST and TRANSPARENCY in support of our COMMUNITIES and

C OLLE C TI V E P URPOSE

In support of this diversity, equity and inclusion vision, we have developed and implemented a multi-year strategic program with a focus on inclusion, education and training.

To help attract talent from a diverse pool of candidates, we post our employment opportunities to state job banks and distribute them to community engaged veteran, minority, women and diversity

organizations. In recent years, to help encourage and foster a workplace with people of all backgrounds, we have partnered with organizations such as the Society of Women Engineers and the National Black MBA Association to distribute targeted job postings.

We maintain a recognition program based on our core values, known as Celebrate, through which we recognize each other's commitment to making a meaningful difference for our patients and

communities and create a shared culture where everyone is responsible for living up to and sustaining our core values.

to Thrive

Since 2018, we have supported an employee resource group - P.O.W.E.R. (Preparing Our Women for Excellence and Results) - open to all Pacira colleagues, focused on promoting leadership values,

fostering a community of support and the advancement of women through professional development and networking opportunities. Quarterly webinars, social events, volunteer activities and a holiday Giving Tree are among the many ways the group provides opportunities for our employees.

We have a cross-functional diversity, equity, and inclusion employee council that serves as an advisory board, comprised of employees who lead, advocate for, inform and communicate our corporate diversity, equity, and inclusion strategic initiatives around four key areas:

Leadership development

Diversity recruiting

Culture

Communication

Additionally, we provide training for our executive team, senior leaders, and managers on Unconscious Bias and Inclusive Leadership.

We believe that a company comprised of a diverse group of talented individuals, with a breadth of different experiences and viewpoints, is essential for success and we are committed to evaluating our people processes to ensure that we are attracting, developing, promoting, and retaining a wide variety of talent.

2024 Corporate Sustainability Report

Global Labor & Human Rights

We strive to promote the labor rights of our employees and human rights where we operate and to make sure that people are treated with regard and consideration, and are dedicated to operating as a strong corporate citizen and to conduct our daily business in alignment with the principles set forth in our Global Labor and Human Rights Policy. We understand that cultivating a positive reputation as a leader in our industry is based on our conduct. We earn our reputation every day by nurturing our relationships with our employees, suppliers, stakeholders, and the communities that we serve.

We are committed to working with and supporting our suppliers, customers, and contractors to uphold the principles stated in this policy and to adopt similar policies within their global operations. Additionally, we aim to follow guidelines set forth in the United Nations Global Compact and the Ten Principles of the United Nations Declaration of Human Rights.

Equal Opportunity and Non-Discrimination

As an equal opportunity employer, Pacira maintains a steadfast policy of non-discrimination with respect to all employees and applicants for employment. Employment decisions are based solely on an applicant's qualifications, merit, and performance and abide by the same principles that guide our vision of diversity and inclusion. Pacira has zero tolerance towards acts of discrimination or harassment of any kind. No penalty may be imposed on an employee, director, contractor, or other stakeholder, as punishment for filing a good faith complaint of discrimination or harassment.

to Thrive

Employee Demographics

employees

1.4%

temporary contract

790

permanent contract

& directly employed

788

Full-time

Part-time

4.1

years average tenure

employees with

10+ years tenure

44.5

years average

workforce age

female 42% 58% male

Women in Executive

Leadership

25%

t director level & above

Racial or Ethnic Diversity

40%

Data as of December 31, 2024

57%

male

43%

female

58%

42%

Compensation and Working Hours

We are dedicated to compensating at a wage that provides an adequate standard of living for all employees and complies with all applicable federal and local wage regulations, including minimum wage and overtime. We believe that excessive working hours may pose a threat to the safety, health, and wellbeing

of our employees and that adequate time off for relaxation and recuperation is necessary for high levels of productivity. We support the health of our employees by encouraging normalized hours of work, rest

periods, paid vacations, and paid holidays. We conduct employee engagement surveys to encourage open feedback and track employee satisfaction.

Total Rewards

In order to attract and retain talent, we maintain broad-based benefits that are provided to all employees, including:

401(k) retirement plan with a matching employer contribution at 100% up to 5% Employee stock purchase plan featuring a 15% discount and lookback feature

1-to-1 sessions with a Certified Financial Planner (CFP) for Retirement and Investment Advice Flexible spending accounts

Medical, dental and vision care plans

Healthcare and dependent care savings accounts

Life insurance, short- and long-term disability policies, and critical illness and accident options Paid vacation, sick time and company holidays, plus a paid day to volunteer in the community Paid parental leave and fertility and maternity assistance

Additionally, we reward employees driving significant value creation with a variety of long-term and short-term incentives, annual performance bonuses, stock options, restricted stock units and a long-term performance cash incentive. We also offer eligible employees tuition assistance towards obtaining an undergraduate degree. We are committed to paying all our employees a fair and living wage.

2024 Corporate Sustainability Report 12

Pay Equity

to Thrive

At Pacira, we are committed to equitable and performance-based compensation practices. We have structured processes in place to help ensure our employees are paid fairly and consistently for similar work, roles, levels, experience, and performance. Our compensation philosophy is also designed to reward high performance and support career growth.

As part of our ongoing efforts, we conduct regular reviews of our pay practices and engage independent experts annually to assess market competitiveness and evaluate pay equity. In 2024, we partnered with an independent third-party expert to conduct a comprehensive pay equity analysis using multiple linear regression. This statistical review evaluated compensation across key factors, including but not limited to experience, role, level, and performance.

The results of the analysis showed no statistically significant differences in pay based on race or gender-indicating that these factors are not predictors of pay at Pacira. The analysis also found a positive correlation between pay and both employee performance and experience, reinforcing our pay-for-performance philosophy and our commitment to recognizing contributions and supporting career development.

We are proud of these results and remain dedicated to maintaining equitable pay practices. We will continue to conduct regular, data-driven reviews and make necessary investments and adjustments as needed.

(Our U.K. location, with a de minimis headcount, was excluded from the analysis.)

2024 Corporate Sustainability Report

Cultivating Growth and Development

We invest in our future leaders by cultivating their growth and development. We regularly assess and identify our emerging talent and support their development with programs, including:

Leadership Development

Executive Coaching

Mentoring

We track turnover and employee engagement among other metrics, conduct mid-year and annual performance reviews for all employees to ensure regular discussions around performance, progress towards goals and professional development, and conduct stay and exit interviews to ensure our talent strategy serves our goal of attracting, developing, and retaining top talent to serve as our future leaders and stewards of our vision.

According to our most recent employee engagement survey, our biggest strengths are our commitment to our product and mission; our employees' relationships with their managers; and people.

At Pacira, we are committed to developing leaders at every level and supporting our employees' career growth. We offer targeted selection training for interviewers to ensure a consistent methodology applied in identifying and hiring the best candidates for open positions and offer critical skills trainings in live and virtual settings, including project management and communications training. We provide robust new hire training, as well as management skills and leadership development training for current and future people leaders. In 2022, we launched LinkedIn Learning, a learning platform with 24/7 access for all employees to a library of resources across an array of leadership and professional topics.

Employee Wellbeing

Pacira is committed to the total wellbeing of our

to Thrive

employees and their families. We offer a range of benefits designed to meet individual needs and help employees and their families live healthy lives. This includes a variety of tools to promote total wellbeing in the areas of health, wealth, work, and life to keep our employees and their families healthy, lower their healthcare costs and reduce stress.

We offer our eligible employees flexible work arrangements-including remote working opportunities, flexible schedules and reduced schedules to help achieve an appropriate work/life balance. Benefits that protect financial wellbeing are also provided, including but not limited to: a paid

parental leave benefit, insurance to help protect assets during times of short- and long-term disability, life insurance and accidental death and dismemberment insurance.

Workplace Safety and Security

We are committed to protecting our employees by providing a workplace that is free from violence, intimidation, harassment, and other unsafe conditions due to internal or external threats. Safeguards for employees are provided as needed and will be maintained and updated with regard for employee security and privacy in accordance with our Code of Business Conduct and Ethics.

We have a formal Environmental Health and Safety (EHS) Program. It is our policy that everyone is entitled to a safe and healthful place to work. We recognize that accident prevention, employee wellness and efficiency of operations are directly related to quality, production and cost. We operate our facilities in a manner that protects the health and safety of our employees.

More details regarding our commitment to workplace safety can be found in our Global Health & Safety Policy.

‌COMMUNITIES & OPIOID-SPARING INNOVATION

We are dedicated to proactive involvement with foundations and local organizations in our communities. When appropriate, we are

Support for

CIENCE

E CHNOL OGY NGINEERING AT H

Initiatives

committed to engaging in discussion with local leaders and stakeholders about Labor Rights, Human Rights, and other community issues. We encourage our employees to give back to their communities and offer one paid day off per year to volunteer. We also encourage our employees to take advantage of company-sponsored volunteer

events and platforms that provide support to local and national causes, such as our Choices Matter platform, which we designed to educate and empower patients around non-opioid options for managing pain. Our commitment to working within communities to raise awareness of the availability of pain management options that can help fight our nation's opioid crisis is discussed in greater detail below.

In October 2022, the Hillsborough County (Florida) Public Schools were awarded a $2 million grant from the United States Department of Defense Education Activity (DoDEA) Program that will

be utilized to institute a STEM Innovation Hub. The grant will serve over 1,500 students offering new coursework centered around inquiry-based learning to increase the number of elementary and middle school students connecting with new STEM opportunities. In July 2023, Pacira launched a collaborative project to support the Hillsborough County Public Schools to engage the Pacira Innovation Center (PIT) in Tampa as a selected STEM Innovation HUB site.

Our first project was hosted in December 2023 when over thirty 8th grade students arrived at the PIT @ Tampa for a day of hands-on technology experience. The students were introduced to Pacira and our mission to provide an opioid alternative to as many patients as possible. Through our mission statement, the students gained an in-depth knowledge of opioid awareness, medical device technology, and training from a controlled setting to patient applications. The class gained insight

on neural anatomy of the human body through a 3-D cadaver experience then divided into rotation

stations covering the technology of ultrasound and applications; live model scanning finding nerves via ultrasound; cryoneurolysis and the making of

COMMUNITIES & OPIOID-SPARING INNOVATION

ice balls to freeze nerves; and use of our broadcast studio to create educational videos.

Our second project was hosted in January 2024, moving STEM education directly to Randal Middle School. The engineering class hosted over 230 students in 7th and 8th grade where each student had an opportunity to spend six days with the Pacira Medical Innovation & Education team where the students developed a real-world biotech module from start to finish.

The students learned about opioid awareness and interacted with the iovera° technology as a baseline

for medical advancement through technology. The students were then tasked with creating their own small business with the goal of enhancing an existing medical device product through research and development and then taking the

steps necessary to get a mock FDA 510(k) approval. Members of our legal, business development, regulatory, and research and development teams interacted with the students to teach them about patents and the planning, science, and processes around a biotechnology product. Together, our partnership has formed a dynamic team, sparking curiosity, innovation, and the skills our youth will need to shape the future.

Expanding access to non- opioid pain managemnt options to redf ine the role of opioids as rescue therapy only

Opioid Reduction Mission

Central to our corporate mission is our commitment to providing an opioid alternative to as many patients as possible using enhanced recovery after surgery ("ERAS") multimodal protocols and opioids for rescue only.

Voices for Non-Opioid Choices

We support Voices for Non-Opioid Choices ("Voices"), a nonpartisan coalition consisting of 100 national and state-level medical, patient advocacy, and addiction and recovery organizations dedicated to preventing opioid addiction by increasing patient access to non-opioid therapies. The Centers for Medicare and Medicaid Services ("CMS") recently issued the proposed Outpatient Prospective Payment System rule for 2023 with EXPAREL continuing to qualify for separate reimbursement for ambulatory surgical centers ("ASC") under reimbursement code C9290. In parallel to our CMS initiatives, we have been supporting bipartisan legislation such as the Non-Opioid Prevent Addiction in the Nation (NOPAIN) Act, intended to expand access to non-opioid options for postsurgical pain relief by providing separate reimbursement in all outpatient environments for Medicare beneficiaries beginning in 2025. NOPAIN was included in the Consolidated Appropriations Act, 2023, which was signed into law by President Joe Biden on December 29, 2022. We are currently supporting initiatives to accelerate the implementation timeline.

340B Pricing Program Expands Access to EXPAREL

In October 2022, we extended the accessibility of EXPAREL to reach significantly more low-income and uninsured patients by participating in the 340B Drug Pricing Program. This federal program allows covered entities to buy EXPAREL at a discount for outpatient procedures and will provide us with the opportunity to provide an opioid-free alternative to financially vulnerable patients where access to opioid-sparing regimens is key.

COMMUNITIES & OPIOID-SPARING INNOVATION

Grants & Corporate Giving

We are dedicated to advancing and improving outcomes for healthcare practitioners and their patients by advancing innovation in non-opioid pain management and regenerative health solutions.

To that end, Pacira provides grants for:

Investigator-initiated trials Independent educational grants

Grants in support of medical missions and charitable donations

Our mission to deliver innovative pain therapies and support pain management extends beyond the borders of the United States and the EU. Since 2019, we have donated vials of EXPAREL to patients in 18 countries across 5 continents that have no alternatives other than opioids. These donations have assisted patients undergoing a range of surgical procedures including hip and knee replacement, wisdom tooth extraction and hernia repair.

United States

Honduras

11 Guyana

Nigeria

Mexico

Nicaragua

Ecuador

Zambia

Guatemala

Cuba

Peru

India

Belize

El Salvador

Haiti

Dominican Republic

Bolivia

Ghana

Palau

1 8 9 10

15 16 18

2 3 5 7

13 14 19

2024 Corporate Sustainability Report

COMMUNITIES & OPIOID-SPARING INNOVATION

Over the past three years we provided support for charitable medical missions in Belize, Honduras, Ghana, Zambia, Guatemala, Ecuador, Mexico, Palau, India, Guyana, Nigeria and the Dominican Republic by donating EXPAREL to help support surgeries for patients in need. We have supported the Louisiana State University Opioid Minimization Initiative as well as a three-year donation grant for Shriners, which in 2024 shipped 1,700 vials of EXPAREL 10mL and 210 vials of 20mL.

Over

8,000 vials of EXPAREL donated

$2M

sin ce 2 0 19

with a commercial value of over

$1,543

Commercial Value

($ in 000's)

10mL

20mL

$831

$447 $405 $416

$314 $330

$82

1,076

1,826

1,224

1,538

# of vials

886

432

3,816 4,332

2022 2023 2024 Since 2019

Today, we completed our 14th surgery in Hermosillo, MX. A special thanks to all of our mission colleagues, the local hospital and St. Andrews Clinic for all you do. Thank you to all of the people that support #childrenssurgeryinternational through your time and donations. This was my tenth time on this mission trip, and I love seeing all of the patients grow up happy and smiling."

Dr. Dan Sampson

Oral Surgeon, Children's Surgery International

On our medical mission to Honduras, our team operated on over 60 people with EXPAREL with perfect success. EXPAREL was directly responsible for not only eliminating the predictable postoperative pain, but actually enabling us to do some surgeries we would have otherwise not been able to do at all because of the complete lack of adequate alternative postopertive pain control options."

Dr. Mark Perlmutter

General Surgeon, Health Volunteers Overseas

2024 Corporate Sustainability Report 19

HOGiLviInDg AreYe

COMMUNITIES & OPIOID-SPARING INNOVATION

In the 2024 holiday season, Pacira was proud to once again partner with the Court Appointed Special Advocates of Morris and Sussex Counties (CASA) on our 3rd annual Giving Tree. This special initiative helps spread joy to children and families who might otherwise not have the opportunity to experience the warmth and magic of the season.

CASA is a nonprofit organization whose mission is to provide a voice for the best interests of vulnerable children who are in foster homes or are under court supervision due to abuse, neglect, or abandonment. The children CASA serves typically come from extreme low-income backgrounds, and many are victims of the opioid epidemic. Our collective goal was to brighten the holiday season of at least 20 local foster children by ensuring they all received presents. Over the past two years, Pacira was able to support over 200 children and families, providing them with everything from toys to essentials.

Pacira was

proud to

partner with to support two of their charitable

initiatives:

For the past 28 years, The Jersey Cares Coat Drive has mobilized the collection and distribution of thousands of "gently used" winter coats to men, women, children, and infants in need. Last year, Jersey Cares collected more than 20,000 coats throughout the state of New Jersey and this

year we can also help support individuals across the state of N.J. to stay warm. In 2024, Pacira contributed over 100 coats.

Jersey Cares collaborates with numerous schools, children's shelters, and community centers to ensure that every child in New Jersey can start the school year with essential supplies. Every year, thousands of under-resourced New Jersey students begin the school year without basic educational tools such as backpacks, notebooks, and calculators. These students face significant challenges in achieving academic success. You

can help support a brighter future for our children by providing these vital resources.

2024 Corporate Sustainability Report 20

202

Disclaimer

Pacira Biosciences Inc. published this content on April 30, 2026, and is solely responsible for the information contained herein. Distributed via Public Technologies (PUBT), unedited and unaltered, on April 30, 2026 at 23:45 UTC.