Niagen Bioscience : May 2026 Investor Presentation

Published: 2026-05-06 19:50:08 ET NAGE

Published on 05/06/2026 at 07:50 pm EDT

Corporate resentation

Nasdaq: NAGE | May 2026

Niagen® Bioscience Mission

We are the global authority on

NAD+ and healthy aging.

We address aging at its root by unlocking the potential of NAD+, a vital coenzyme that declines with age.

We developed Niagen®, thє most єrficiєnt, high-quality NAD+ booster, and Tru Niagen®, the 1 NAD+ healthy aging supplement in the U.S.1, as well as the Niagen Plus product portfolio for advanced delivery formats including infusions and injections.

1 Based on the top-selling dietary supplement brands by revenue per the largest U.S. e-commerce marketplace

Highlights

Significant markєt opportunity in human and pet nutrition, IV and injectables, cosmetics and pharmaceuticals

100+ patents

Strong intellectual property portfolio for Niagen® and other NAD+ precursors

Strong Balance Sheet

Q1 2026 (LTM):

$130.4m in Revenues

$18.6m in Net Income

$66.5m in Cash, no Debt

Strategic partnerships

with blue chip companies

Demographic Shifts Support

Clinical Research Advancing Broadly in NAD+

Gen Z and Millennials drive 41% of wellness spend; $500B U.S. wellness market expected to grow 4-5% annually1

Broad pipeline of clinical trials studying NAD+ with most promise in rare and orphan diseases

1 Refer to https://www.mckinsey.com/industries/consumer-packaged-goods/our-insights/future-of-wellness-trends

Clinical studies have established Nicotinamide Adenine Dinucleotide (NAD+) as a vital co-enzyme for cellular defense and repair

NAD+ is important for energy production and is shown to help cells repair during recovery, sickness, and aging

Niagen Bioscience's patented NAD+ boosting supplement, nicotinamide riboside, has been clinically proven to increase NAD+ levels, while NAD+ itself does not elevate NAD levels

D I D Y O U K N O W ?

NAD+ Declines by up to ~65% between the ages of 30 and 70 1

Tissue NAD+

Decline

Age 30 Age 70

1 Massudi et al., 2012; Janssens et al., 2022 | Based on analysis of human skin and muscle tissue.

NAD+

NR is a naturally occurring form of vitamin B3.

Only NR can enter cells directly. NR is then converted into NAD+ through an єrficiєnt two step pathway.

We have commercialized NR as a nutritional supplement (Niagen®) and pharma-grade treatment (Niagen IV and injections).

Figure 1. Chemical structures and biosynthetic pathway of NR, NMN, and NAD+. Two mammalian nicotinamide riboside kinases (NRK1, NRK2) use ATP to convert NR into NMN. Nicotinamide mononucleotide adenylytransferases (NMNAT1-3 use ATP to convert NMN into NAD+. Only NR can enter cells directly.

Scientific Advisory Board

Čuides Our Research-Driven Approach

NOBEL PRIZE WINNER | CHEMISTRY

Charles Brenner, Ph.D.

Roger Kornberg, Ph.D.

Rudolph Tanzi, Ph.D.

Bruce German, Ph.D.

Dr. Pinchas Hassy Cohen

Brunie H. Felding, Ph.D.

Dr. Vilhelm (Will) Bohr, M.D., Ph.D., D.Sc.

Alfred E Mann Family

Professor of Structural

Kennedy Professor of

Chairman of Food,

Dean & Professor of

Associate Professor of

Professor in Genome

Foundation Chair,

Biology

Neurology

Nutrition, & Health

Gerontology, Medicine

Molecular Medicine

Instability and

Department of Diabetes

Stanford University

Harvard University

University of

and Biological Sciences

Scripps Research

Neurodegeneration,

& Cancer Metabolism

California, Davis

University of Southern

Institute

Department of Cellular

City of Hope

Nobel Prize Winner,

Leading Alzheimer's

California

and Molecular Medicine,

Chemistry, 2006

Researcher, TIME 100

Leader in Food, Nutrition,

Renowned Breast Cancer

University of

World's Foremost

Most Inﬂuєntial 2015

& Wellness Innovation

Aging expert with

Researcher focused on

Copenhagen.

Authority on NAD+

pioneering research and

NAD+ supplementation

Metabolism

discoveries on

One of the world's most

mitochondria and novel

published researchers

microproteins

on aging and

neurodegenerative

disease

NAD+ Increasingly Recognized As a

A Doctor's Guide to Longevity Supplements and Aging Well

Biotech Meets Longevity Niagen Biosciєncє Rєdєfinєs Aging Through NAD+ Science

NAD Supplements Promise to Improve Energy, Metabolism, and Longevity[…]

NAD+ is generating serious buzz

Kendall Jenner

Kourtney Kardashian

BRIANNA PETERS | FEBRUARY 2, 2026 SARA KITNICK | APRIL, 2026

MAHALIA CHANG | FEBRUARY 27, 2026

Justin & Hailey Bieber

Jennifer Aniston

Chrissy Teigen

John Legend

Joe Rogan

The Secrets to Celebrities' Red-Carpet Glow

Shoot It Into My Veins: What's Fueling the Vitamin IV Craze

109: How To Boost NAD Lєvєls To Fight Inﬂammation, Improve Recovery, and Slow Aging

Andrew Huberman

Tom Brady

Aaron Judge

Shannon Sharpe

Numerous professional sports

TATIANA BONCOMPAGNI | MARCH 14, 2026 MELISSA ANGELL | MARCH 4, 2026

DR. RHONDA PATRICK & DR. CHARLES BRENNER

| FEBRUARY 10, 2026

teams

Addressing a arge and Črowing ongevity and

Wellness Market

$85B 60%

global anti-aging market in 2025, expected to surpass $120 billion by 2030, growing at a CAGR of 7% from 2025-2030 1

share of consumers across markets report that healthy aging is a 'top' or 'very important' priority 2

84% 41%

of U.S. consumers say wellness is a 'top' or 'important' priority 3

younger generations are spending disproportionately on wellness - Gen Z and Millennials drive 41% of wellness spend 4

1 https://gabelli.com/research/the-longevity-boom-opportunities-in-anti-aging/

3 https://www.mckinsey.com/industries/consumer-packaged-goods/our-insights/future-of-wellness-trends

2 https://gabelli.com/research/the-longevity-boom-opportunities-in-anti-aging/

4 https://www.mckinsey.com/industries/consumer-packaged-goods/our-insights/future-of-wellness-trends

ortfolio of Rapidly Črowing Branded

C O N S U M E R H E A L T H

I V & I N J E C T A B L E S

S K I N C A R E

Pro

Immune

Foundation

Beauty

Infusions

Injectables

Consumer Health

Thє most єrficiєnt way to sarєly єlєvatє NAD+ levels and the only legal and patented form of nicotinamide riboside chloride (Niagen®) available in the world.

Tru Niagen® is Scientifically

Tru Niagen® Increases NAD+ by 40-50% After 8 Weeks 1

% Change in NAD+ Levels

-20

+48%

-14%

Placebo

(No Niagen®)

Niagen®

40+

Human Clinical Studies

50+

Patents

500+

Publishєd Sciєntific Studiєs

300+

Global Research Collaborations

1 Conze et al., 2019 | On average at 300 mg / day for 8 weeks

Expanding Člobal Distribution Footprint and artnering with Blue Chip Companies

Key Tru Niagen®

B2B Distributors / Retail artners

Key Niagen® Ingredient artners

IV & Injectables

Targeting NAD+ IV and Injections Market valued at approx. $300M 1

Through Niagen lus

Niagen IV and Injectables

Pharma-grade Niagen Plus products improve administration time, minimize side effects and quality concerns compared to current NAD+ IV solutions

Authorized for use in the U.S. FDA 503B Category 1 List

New at-home injection product via clinician-directed telehealth platform under Niagen Plus

1 https://www.datainsightsmarket.com/reports/nad-intravenous-therapy-300554?tab=summary

Niagen IV is a Superior Solution to NAD+ IV and Has the

NAD+ IV

Up to 75% faster infusion time1,2

Blood NAD+ levels peaking sooner and higher three hours post-infusion 1

Minimal side effects1,2

Pharmaceutical grade Niagen®

Niagen IV is not only set up to replace NAD+ IV, but also has the potential to expand the market to new consumers who have been hesitant to experience NAD+ IV due to its many drawbacks

1 https://www.medrxiv.org/content/10.1101/2024.06.06.24308565vl

2 https://www.frontiersin.org/journals/aging/articles/10.3389/fragi.2026.1652582/full

Niagen IV Is Seeing Strong Early Adoption, and Our Expanding

1,500+ clinics onboarded since launch in August 2024

$6.4m in ingredient sales of

pharmaceutical-grade Niagen® since launch

Partnered with leaders in the industry

to bring Niagen IV to customers nationwide

Skincare

Niagen® Skincare Innovation ab

Niagen NanoCloud

Extending NAD+ Science into Skincare

First and only topical skincare powered by patented Niagen®

Propriєtary watєrlєss nanofibєr sachєt eliminates the degradation problem that undermines all water-based NAD+ skincare products

Skin bєnєfits within 2 wєєks1

Smoother

More hydrated

Younger-looking

1 Based on a 6-week consumer perception study of 37 female participants aged 35+ using product 2x daily

Disclaimer

Niagen Bioscience Inc. published this content on May 06, 2026, and is solely responsible for the information contained herein. Distributed via Public Technologies (PUBT), unedited and unaltered, on May 06, 2026 at 23:47 UTC.