Seer, Inc. Announces Launch of New Proteograph Product Suite

Published: 2025-05-29 08:06:22 ET SEER

Published on 05/29/2025 at 08:06

Seer, Inc. announced the launch of its new Proteograph®? Product Suite, featuring the Proteograph ONE Assay and SP200 Automation Instrument-- its most advanced solution yet for scalable, high-resolution, mass spec-based proteomics. Seer's newest innovation, debuting at the upcoming American Society for Mass Spectrometry (ASMS) annual conference in Baltimore, MD, overcomes the challenges of large-scale proteomic studies that had been hindered by limited throughput and prohibitive costs.

It significantly enhances the Proteograph Product Suite's ability to achieve the throughput, efficiency, and depth required for the world's first true population-scale deep, unbiased proteomic studies. With the new Proteograph workflow, Seer achieves a transformative milestone by significantly improving the scalability, reproducibility, and affordability of deep proteomic analysis. These advancements push the boundaries of the original capabilities of the Proteograph Product Suite launched in 2021, addressing historical industry-wide limitations where deep workflows faced challenges scaling efficiently, manual handling introduced variability, and large-scale studies were hindered by prohibitive costs.

The streamlined Proteograph workflow processes more than 1,000 samples per week on a single SP200 instrument, enabling mass-spec based proteomic analysis at a depth, speed and scale that were previously not possible. The new offering also takes advantage of operational efficiencies and Seer's volume-based pricing model to reduce the per-sample cost of proteomic analysis by about 60% compared to the company's initial release of the Proteograph Product suite in 2021. These advancements bring population-scale mass spec proteomics into practical reach, enabling large-scale biomarker discovery, longitudinal disease studies, and comprehensive multi-center research.

Proteograph insights increasingly drive advances in personalized medicine, capturing biological context that is impossible with genomics or transcriptomics alone. Seer's Proteograph workflow overcomes longstanding barriers to deep, unbiased proteomics, empowering researchers to explore the complexity of the proteome at a speed, cost, and scale previously unimaginable. Key Capabilities of the New Proteograph Product Suite: Higher Throughput: Processes over 1,000 samples per week per SP200 instrument--doubling throughput without a tradeoff in performance; Operational Efficiency: Streamlined workflow helps lower per-sample analysis cost by about 60% since 2021; Automated Workflow: Reduces operator-induced variability and adds unmatched robustness for the processing of valuable biological samples; Faster Turnaround: Automated run time of under 5 hours, enabling 80-sample batches to be completed comfortably within an 8-hour shift; Deep, Unbiased Analysis: Identifies up to 10 times more proteins than traditional mass spec workflows.

In addition to the product launch, Seer and its collaborators will unveil new scientific data at ASMS 2025, showcasing the transformative impact of the Proteograph product Suite in Alzheimer's disease, cancer, and drug development research. A breakfast seminar featuring renowned proteomics experts Professors Josh Coon and Gary Patti will present compelling findings from their early access experience with the Proteograph ONE workflow.