4D Molecular Therapeutics : Goldman Sachs 2025 presentation (6591c3)

FDMT

Published on 06/11/2025 at 13:13

Goldman Sachs 2025 Healthcare Conference

Corporate Presentation June 2025

© 2025 4D Molecular Therapeutics. All Rights Reserved.

© 2025 4D Molecular Therapeutics. All Rights Reserved.

4D-150 Key Updates

4D-150

Over 50 clinical trial sites activated to date

RMAT: Regenerative Medicine Advanced Therapy designation

Multi-Billion Dollar

Annual Opportunity

$17B+ and growing global market

Leveraging expression of validated blockbuster aflibercept

4D-150

Addresses Primary

Clinical Unmet Need

Topline Data from wet AMD Pivotal Trials in 2027

Readouts from both Phase 3 studies in 4FRONT global registration program expected in H2 2027

Ease of Clinical & Commercial Adoption

Favorable Safety Profile

Single IVT injection: Seamless integration into retina clinic practice flow and buy & bill reimbursement model

Predictable long-term safety:

Clinically significant IOI rate in-line with aflibercept bolus (remains standard-of-care, >64M eyes treated)

Backbone therapy with multi-year durability: Foundational therapy with paradigm-shifting treatment burden reduction & vision preservation

Multi-Billion Dollar

Annual Opportunity

$17B+ and growing global market

Leveraging expression of validated blockbuster aflibercept

4D-150

Addresses Primary

Clinical Unmet Need

Topline Data from wet AMD Pivotal Trials in 2027

Readouts from both Phase 3 studies in 4FRONT global registration program expected in H2 2027

Ease of Clinical & Commercial Adoption

Favorable Safety Profile

Single IVT injection: Seamless integration into retina clinic practice flow and buy & bill reimbursement model

Predictable long-term safety:

Clinically significant IOI rate in-line with aflibercept bolus (remains standard-of-care, >64M eyes treated)

Backbone therapy with multi-year durability: Foundational therapy with paradigm-shifting treatment burden reduction & vision preservation

Disclaimer

4D Molecular Therapeutics Inc. published this content on June 11, 2025, and is solely responsible for the information contained herein. Distributed via Public Technologies (PUBT), unedited and unaltered, on June 11, 2025 at 17:12 UTC.