Vertex Pharmaceuticals Incorporated : 2024 Data Summary (2024 Vertex Data Summary)

VRTX

Vertex Pharmaceuticals

DATA SUMMARY

We monitor and report metrics in areas that align with our corporate responsibility priorities. The table below discloses our three-year progress on select indicators.

METRIC

2024

2023

2022

Business and Ethics

R&D Investment (GAAP, in USD thousands)

8,258,7001

3,690,000

2,655,800

R&D Investment as a Percentage of Business Operating Expenses (GAAP)

85%

77%

74%

% of Employees Who Completed Their Annual Code of Conduct Training

100%

100%

100%

% Spend on Small Businesses2

17.3%

18.1%

18.6%

Workplace

Total Employees Globally (approximate)

6,100

5,100

4,800

New Hires Globally (approximate)

1,100

1,100

1,000

Voluntary Turnover Rate (Global, Trailing 12 Months Metric)

4.4%

4.7%

8.7%

Community

Nonprofits Supported Through Matching Gift Program

2,592

2,183

1,895

Hours Volunteered by Employees During Work Time

12,715

10,013

7,845

% of Employees Who Volunteered on Global Day of Service

70%

60%

57%

Environment, Health, Safety and Sustainability

TRIR (per 200,000 hours worked)3

0.18

0.33

0.24

DART (per 200,000 hours worked)3

0.16

0.15

0.15

3 ERM CVS provided limited assurance of safety rates (TRIR, DART) for 2020-2024. Assurance information for 2020-2023 can be found in the associated corporate responsibility (CR) reports. The 2024 ERM CVS Assurance Report and Basis of Reporting can be viewed at www.vrtx.com/responsibility/policies-positions-and-reports.

Vertex 2024 Corporate Responsibility Report | 1

METRIC

2024

2023

2022

% Square Feet of Buildings Operated That Are Green Certified

79%4

82%4

83%

Total GHG Emissions Scope 1 & Scope 2 Market-Based (metric tons CO e)5,6

12,906

13,198

13,620

2

GHG Scope 1 (metric tons CO2e)5

8,976

8,311

9,334

GHG Scope 2 (metric tons CO2e)5,6

3,930

4,888

4,285

GHG Scope 3 (metric tons CO2e)

551,647

474,129

249,816

CDP Climate Change Survey Score

B

A-

B

% Energy From Renewable Sources

50%

49%

N/A

Total Waste (metric tons)5,7

1,982

1,689

1,308

Nonhazardous Waste (metric tons)5,7

1,467

1,212

879

Nonhazardous Waste Diverted From Landfill (metric tons)5,7

596.7

403.1

372.3

% Nonhazardous Waste Recycled or Composted5,7

41%

33%

42%

Hazardous Waste (metric tons)5,7

514.7

476.9

428.9

Laboratory and Manufacturing Waste Recycled (metric tons)5

130.0

119.6

89.3

% Total Waste Diverted From Landfill5,7,8

57%

52%

60%

Total Water Withdrawn (megaliters)9

137.8

169.3

160.6

Vertex 2024 Corporate Responsibility Report | 2

Disclaimer

Vertex Pharmaceuticals Incorporated published this content on April 15, 2025, and is solely responsible for the information contained herein. Distributed via , unedited and unaltered, on April 15, 2025 at 18:20 UTC.