BridgeBio Reports First Quarter 2026 Financial Results and Corporate Updates

Published: 2026-05-07 16:01:04 ET BBIO

Published on 05/07/2026 at 04:01 pm EDT

PALO ALTO, Calif., May 07, 2026 (GLOBE NEWSWIRE) -- BridgeBio Pharma, Inc. (Nasdaq: BBIO) (“BridgeBio” or the “Company”), a commercial-stage, multi-product biopharmaceutical company focused on developing medicines for genetic conditions, announced today its financial results for the first quarter ended March 31, 2026, and provided an update on Attruby’s commercial progress.

Pipeline Overview:

“I’m excited for the opportunity to begin educating on the differentiation we are seeing in the real world with Attruby, which is consistent with its biochemical differentiation. Furthermore, the company is in a period of focused execution, and I anticipate efficient filing, approval, and pre-commercial activities over the coming 12 months setting us up for three critical launches. Finally, because the company is fully financed but trading at a deep discount to intrinsic value, we think it prudent to begin share buybacks which at this point offer an attractive risk-adjusted return relative to other uses of capital,” said Neil Kumar, Ph.D., Co-Founder and CEO of BridgeBio.

Commercial Updates:

The first quarter total revenues, net totaled $194.5 million, comprised of $180.6 million of U.S. Attruby net product revenue, $9.5 million from royalty revenue, and $4.4 million in license and services revenue.

"This was another strong quarter for Attruby, highlighting the continued durable growth trajectory for use in ATTR-CM by physicians compounding quarter over quarter," said Matt Outten, Chief Commercial Officer of BridgeBio. "Beyond Attruby, we have assembled commercial teams for LGMD2I/R9, ADH1, and achondroplasia, preparing to serve these communities from day one. We have a commercial organization that knows how to launch, how to scale, and how to build, and we are just getting started."

Pipeline Updates:

Attruby (acoramidis) – First and only near-complete (≥90%) transthyretin (TTR) stabilizer for treatment of transthyretin amyloid cardiomyopathy (ATTR-CM):

BBP-418 – Glycosylation substrate for limb-girdle muscular dystrophy type 2I/R9 (LGMD2I/R9):

________________________________1 https://jamanetwork.com/journals/jamacardiology/fullarticle/28470552 https://investor.bridgebio.com/news/news-details/2026/BBP-418-Demonstrates-Consistent-Efficacy-and-Favorable-Safety-Profile-in-Phase-3-FORTIFY-Interim-Analysis-in-LGMD2IR9/default.aspx

Encaleret – Calcium-sensing receptor (CaSR) antagonist for autosomal dominant hypocalcemia type 1 (ADH1) and chronic hypoparathyroidism:

Infigratinib – FGFR3 inhibitor for achondroplasia and hypochondroplasia:

Share Buyback Program:

The Board of Directors has approved a stock repurchase program on May 6, 2026 pursuant to which the Company may purchase up to $500 million of the Company’s outstanding common stock. Stock repurchases under the program may be made from time to time, in the open market, in privately negotiated transactions and otherwise, at the discretion of management of the Company and in accordance with applicable federal securities laws, including Rule 10b-18 of the Securities Exchange Act, of 1934, as amended, and other applicable legal requirements. The timing, pricing, and amounts of these repurchases will depend on a number of factors, including the market price of the Company’s common stock and general market and economic conditions. The stock repurchase program does not obligate the Company to repurchase any dollar amount or number of shares, and the program may be suspended or discontinued at any time.

Financial Updates:

Cash, Cash Equivalents and Marketable Securities

Cash, cash equivalents and marketable securities totaled $940.2 million and $587.5 million as of March 31, 2026 and December 31, 2025, respectively.

Total Revenues, Net

Total revenues, net for the three months ended March 31, 2026 were $194.5 million compared to $116.6 million for the same period in 2025. The $77.9 million increase was primarily driven by a $143.9 million increase in net product revenue from Attruby, and a $9.3 million increase in royalty revenue primarily earned from net product sales of BEYONTTRA in the EU and Japan. These increases were partially offset by a decrease in license and services revenue primarily due to recognition of $75.0 million of milestone-related revenue in 2025.

Total Operating Costs and Expenses

Total operating costs and expenses for the three months ended March 31, 2026 were $300.5 million, compared to $221.0 million for the same period in 2025. The $79.5 million increase was primarily driven by a $57.5 million increase in selling, general and administrative (SG&A) expenses, reflecting continued investment in the ongoing commercialization of Attruby, pre-commercial activities for BridgeBio's Phase 3 product candidates, a $7.3 million increase in total cost of revenues primarily due to the product costs of Attruby, and a $15.2 million increase in R&D expenses to support the development of late-stage programs.

Stock-based compensation expenses included in operating costs and expenses for the three months ended March 31, 2026 were $33.4 million, of which $20.3 million, $12.1 million, and $1.0 million were included in SG&A expenses, R&D expenses, and cost of goods sold, respectively. Stock-based compensation expenses included in operating costs and expenses for the same period in 2025 were $29.4 million, of which $18.0 million, $11.3 million, and $0.1 million were included in SG&A expenses, R&D expenses, and cost of goods sold, respectively.

Total Other Expense, Net

Total other expense, net for the three months ended March 31, 2026, was $(60.6) million compared to $(65.2) million for the same period in 2025.

The change in total other expense, net of $4.6 million for the three months ended March 31, 2026, compared to the same period in 2025 was primarily driven by a $15.9 million increase in noncash interest expense related to deferred royalty obligations and a $2.7 million increase in net loss from equity method investments. These increases were partially offset by a $21.2 million decrease in loss on extinguishment of debt recognized in 2025 and a $5.2 million decrease in interest expense.

Net Loss Attributable to Common Stockholders of BridgeBio and Net Loss per Share

For the three months ended March 31, 2026, the Company recorded a net loss attributable to common stockholders of BridgeBio of $164.0 million compared to $167.4 million for the same period in 2025.

For the three months ended March 31, 2026, the Company reported a net loss per share of $0.84 compared to $0.88 for the same period in 2025.

(1)     Including a related party amount of $(5,361) for the three months ended March 31, 2026.

(1)     The condensed consolidated balance sheet of December 31, 2025 is derived from the audited consolidated financial statements as of that date.(2)     Including related party amounts of $3,622 and $2,003 as of March 31, 2026 and December 31, 2025, respectively.(3)     Including related party amounts of $206,377 and $204,650 as of March 31, 2026 and December 31, 2025, respectively.

(1)     Including a related party amount of $5,361 for the three months ended March 31, 2026.(2)     Including a related party amount of $3,622 for the three months ended March 31, 2026.(3)     Including a related party amount of $(2,024) for the three months ended March 31, 2026.

Webcast InformationBridgeBio will host a conference call and webcast to discuss first quarter financial results today, May 7, 2026, at 4:30 pm ET. This event can be accessed at https://events.q4inc.com/attendee/635926690 or by visiting the “Events & Presentations” page within the Investors section of the BridgeBio website at http://investor.bridgebio.com. A replay of the webcast will be available on the BridgeBio website for 30 days following the event.

About Attruby® (acoramidis)INDICATIONAttruby is a transthyretin stabilizer indicated for the treatment of the cardiomyopathy of wild-type or variant transthyretin-mediated amyloidosis (ATTR-CM) in adults to reduce cardiovascular death and cardiovascular-related hospitalization.

IMPORTANT SAFETY INFORMATIONAdverse ReactionsDiarrhea (11.6% vs 7.6%) and upper abdominal pain (5.5% vs 1.4%) were reported in patients treated with Attruby versus placebo, respectively. The majority of these adverse reactions were mild and resolved without drug discontinuation. Discontinuation rates due to adverse events were similar between patients treated with Attruby versus placebo (9.3% and 8.5%, respectively).

About BridgeBio Pharma, Inc.BridgeBio exists to develop transformative medicines for genetic conditions. Millions of people worldwide living with genetic conditions lack treatment options, often because drug development for small patient populations can be commercially challenging. We aim to bridge the gap between advancements in genetic science and meaningful medicines for underserved patient populations. Our decentralized, hub-and-spoke model is designed for speed, precision, and scalability. Autonomous and empowered teams focus on individual conditions, while a central hub provides the clinical, regulatory, and commercial capabilities needed to bring innovation to market. For more information, visit bridgebio.com and follow us on LinkedIn, X, Facebook, Instagram, YouTube, and TikTok.

BridgeBio Pharma, Inc. Forward-Looking StatementsThis press release contains forward-looking statements. Statements in this press release may include statements that are not historical facts and are considered forward-looking within the meaning of Section 27A of the Securities Act of 1933, as amended (the Securities Act), and Section 21E of the Securities Exchange Act of 1934, as amended (the Exchange Act), which are usually identified by the use of words such as “anticipates,” “believes,” “continues,” “estimates,” “expects,” “hopes,” “intends,” “may,” “plans,” “projects,” “remains,” “seeks,” “should,” “will,” and variations of such words or similar expressions. BridgeBio intends these forward-looking statements to be covered by the safe harbor provisions for forward-looking statements contained in Section 27A of the Securities Act and Section 21E of the Exchange Act. These forward-looking statements, including express and implied statements relating to the continued commercial success of Attruby/Beyonttra (acoramidis) and the safety, efficacy, biochemical profile, real-world differentiation, and market potential of Attruby/Beyonttra; the Company’s expectations regarding timing of regulatory submissions, approvals and commercial launches, including for BBP-418 in LGMD2I/R9, encaleret in ADH1, and infigratinib in achondroplasia; the Company’s expectations regarding the timing and outcome of pre-commercial activities and its ability to execute on its operational priorities over the coming 12 months, including activities designed to support three critical launches; the timing of the Company’s clinical trials and milestones for its various programs, including for ATTR-CM; the eligibility of BBP-418 under the Rare Pediatric Priority Review Voucher (PRV) program and related FDA review timeline; the advantages of the Company’s business model and overall strategy; the potency, safety and the potential benefits of the Company’s product and product candidates; and the Company’s anticipated share buyback program, including the Company’s views regarding the attractiveness of share repurchases as a use of capital and the value of its common stock relative to the Company’s assessment of intrinsic value. Such statements reflect the Company’s current views about the Company’s plans, intentions, expectations and strategies, which are based on the information currently available to it and on assumptions the Company has made. Although the Company believes that its plans, intentions, expectations and strategies as reflected in or suggested by those forward-looking statements are reasonable, the Company can give no assurance that the plans, intentions, expectations or strategies will be attained or achieved. Furthermore, actual results may differ materially from those described in the forward-looking statements and will be affected by a number of risks, uncertainties and assumptions, including, but not limited to, initial and ongoing data from the Company’s preclinical studies and clinical trials not being indicative of final data, the potential size of the target patient populations the Company’s product candidates are designed to treat not being as large as anticipated, the design and success of ongoing and planned clinical trials, future regulatory filings, approvals and/or sales, despite having ongoing and future interactions with the FDA or other regulatory agencies to discuss potential paths to registration for the Company’s product candidates, the FDA or such other regulatory agencies not agreeing with the Company’s regulatory approval strategies, components of the Company’s filings, such as clinical trial designs, conduct and methodologies, or the sufficiency of data submitted, the Company’s pre-commercial activities, commercial launches or operational execution not occurring on anticipated timelines or not supporting planned launches as expected, real-world experience with Attruby/Beyonttra not being consistent with observed biochemical differentiation or not translating into differentiated clinical, commercial or market outcomes, the continuing success of the Company’s collaborations, the Company’s ability to obtain additional funding, including through less dilutive sources of capital than equity financings, potential volatility in the Company’s share price, the Company’s share repurchase program being modified, suspended or discontinued, or share repurchases not delivering the anticipated benefits or proving to be a more attractive use of capital than other alternatives, the impacts of current macroeconomic and geopolitical events, including changing conditions from hostilities in Ukraine and the Middle East, increasing rates of inflation and changing interest rates, on business operations and expectations, as well as those risks set forth in the Risk Factors section of the Company’s most recent Quarterly Report on Form 10-Q and Annual Report on Form 10-K and the Company’s other filings with the U.S. Securities and Exchange Commission. Moreover, the Company operates in a very competitive and rapidly changing environment in which new risks emerge from time to time. These forward-looking statements are based upon the current expectations and beliefs of the Company’s management as of the date of this press release, and are subject to certain risks and uncertainties that could cause actual results to differ materially from those described in the forward-looking statements. Except as required by applicable law, BridgeBio assumes no obligation to update publicly any forward-looking statements, whether as a result of new information, future events or otherwise.

BridgeBio Media Contact:Bubba Murarka, Executive Vice [email protected](650)-789-8220

BridgeBio Investor Contact:Chinmay Shukla, Senior Vice President, Strategic [email protected]